Mild Rhodium(III)-Catalyzed C鈥揌 Allylation with 4-Vinyl-1,3-dioxolan-2-ones: Direct and Stereoselective Synthesis of (E)-Allylic Alcohols
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- 作者：Shang-Shi Zhang ; Jia-Qiang Wu ; Ye-Xing Lao ; Xu-Ge Liu ; Yao Liu ; Wen-Xin Lv ; Dong-Hang Tan ; Yao-Fu Zeng ; Honggen Wang
- 刊名：Organic Letters
- 出版年：2014
- 出版时间：December 19, 2014
- 年：2014
- 卷：16
- 期：24
- 页码：6412-6415
- 全文大小：414K
- ISSN：1523-7052
文摘
A rhodium(III)-catalyzed C鈥揌 direct allylation reaction with 4-vinyl-1,3-dioxolan-2-ones has been developed. The reaction provides a facile and stereoselective access to substituted-(E)-allylic alcohols under mild and redox-neutral reaction conditions. Olefinic C鈥揌 activation is applicable, giving multifunctionalized skipped dienes in good yields. Minimal double-bond migration was observed.