Understanding the Colloidal Stability of the Mesoporous MIL-100(Fe) Nanoparticles in Physiological Media
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- 作者：Elena Bellido ; Mazheva Guillevic ; Tania Hidalgo ; Manuel J. Santander-Ortega ; Christian Serre ; Patricia Horcajada
- 刊名：Langmuir
- 出版年：2014
- 出版时间：May 27, 2014
- 年：2014
- 卷：30
- 期：20
- 页码：5911-5920
- 全文大小：453K
- 年卷期：v.30,no.20(May 27, 2014)
- ISSN：1520-5827
文摘
The colloidal and chemical stability of nanoparticles of the nontoxic and biodegradable iron(III) trimesate MIL-100(Fe) nanocarrier have been evaluated in the presence of a series of simulated physiological fluids for intravenous and oral administration. MIL-100(Fe) nanoparticles exhibit an appropriate colloidal stability and biodegradability, mainly dependent on both the nature of their physicochemical surface and the media composition, being a priori compatible with their biomedical use.