Benzaldehyde-Functionalized Polymer Vesicles

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• 作者：Guorong Sun ; Huafeng Fang ; Chong Cheng ; Peng Lu ; Ke Zhang ; Amy V. Walker ; John-Stephen A. Taylor ; Karen L. Wooley
• 刊名：ACS Nano
• 出版年：2009
• 出版时间：March 24, 2009
• 年：2009
• 卷：3
• 期：3
• 页码：673-681
• 年卷期：0
• ISSN：1936-086X

文摘

Polymer vesicles with diameters of ca. 100−600 nm and bearing benzaldehyde functionalities within the vesicular walls were constructed through self-assembly of an amphiphilic block copolymer PEO₄₅-b-PVBA₂₆ in water. The reactivity of the benzaldehyde functionalities was verified by cross-linking the polymersomes and also by a one-pot cross-linking and functionalization approach to further render the vesicles fluorescent, each via reductive amination. In vitro studies found these labeled nanostructures to undergo cell association.