Copper(II)-Catalyzed Carbon鈥揅arbon Triple Bond Cleavage of Internal Alkynes for the Synthesis of Annulated Indolizines
详细信息 查看全文
- 作者：Jinwei Sun ; Fuyao Wang ; Huayou Hu ; Xiangshan Wang ; Hui Wu ; Yun Liu
- 刊名：Journal of Organic Chemistry
- 出版年：2014
- 出版时间：May 2, 2014
- 年：2014
- 卷：79
- 期：9
- 页码：3992-3998
- 全文大小：382K
- 年卷期：v.79,no.9(May 2, 2014)
- ISSN：1520-6904
文摘
Cleavage of C鈮 bond in butynedioates via copper(II)-catalyzed reaction has been achieved, leading to the synthesis of benzo[f]pyrido[1,2-a]indole-6,11-diones in high yields by one-pot three-component reactions. In this unprecedented C鈮 bond cleavage reaction of internal alkynes, both fragments from the alkyne are successively incorporated into the products.