Br酶nsted Acid-Catalyzed Decarboxylative Redox Amination: Formation of N-Alkylindoles from Azomethine Ylides by Isomerization

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• 作者：Hui Mao ; Sichang Wang ; Peng Yu ; Huiqing Lv ; Runsheng Xu ; Yuanjiang Pan
• 刊名：Journal of Organic Chemistry
• 出版年：2011
• 出版时间：February 18, 2011
• 年：2011
• 卷：76
• 期：4
• 页码：1167-1169
• 全文大小：720K
• 年卷期：v.76,no.4(February 18, 2011)
• ISSN：1520-6904

文摘

A Br酶nsted acid-catalyzed decarboxylative redox amination involving aldehydes with 2-carboxyindoline for the synthesis of N-alkylindoles is described. The decarboxylative condensations of aldehydes with 2-carboxyindoline produce azomethine ylides in situ, which then transform into N-alkylindoles by isomerization.