Tailoring MgxMn1鈥?i>xFe2O4 Superparamagnetic Nanoferrites for Magnetic Fluid Hyperthermia Applications

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• 作者：Minhong Jeun ; Sungwook Park ; Gun Hyuk Jang ; Kwan Hyi Lee
• 刊名：ACS Applied Materials & Interfaces
• 出版年：2014
• 出版时间：October 8, 2014
• 年：2014
• 卷：6
• 期：19
• 页码：16487-16492
• 全文大小：448K
• ISSN：1944-8252

文摘

A superparamagnetic nanoferrite (SPNF) with high magnetic moment, AC magnetically induced heating (AC-heating) capacity, and good biocompatibility is the most vital part of magnetic fluid hyperthermia for utilizing it in the clinics. Herein, we precisely tune magnetic properties and AC-heating characteristics of Mg_xMn_1鈥?i>xFe₂O₄ SPNF via chemically controlling the cations鈥?concentration and distribution to develop a tailored Mg_xMn_1鈥?i>xFe₂O₄ SPNF as a potential magnetic fluid hyperthermia agent. The magnetic and AC-heating characteristics of the tailored Mg_xMn_1鈥?i>xFe₂O₄ SPNF are strongly dependent on the Mg/Mn cations鈥?concentration and distribution, and Mg_0.285Mn_0.715Fe₂O₄ SPNF exhibits the highest saturation magnetization and AC-heating capacity as well as high biocompatibility.

Keywords:

nanoferrite; superparamagnetic particle; MgMnFe₂O₄; nanofluid; magnetic hyperthermia