Highly Stereoselective Vinylogous Pummerer Reaction Mediated by Me3SiX

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• 作者：Jose L. Garc&iacute ; a Ruano ; José ; Alemá ; n ; M. Teresa Aranda ; Mar&iacute ; a J. Aré ; valo ; and Albert Padwa
• 刊名：Organic Letters
• 出版年：2005
• 出版时间：January 6, 2005
• 年：2005
• 卷：7
• 期：1
• 页码：19 - 22
• 全文大小：78K
• 年卷期：v.7,no.1(January 6, 2005)
• ISSN：1523-7052

文摘

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A highly stereoselective vinylogous Pummerer rearrangement involving 1,4-migration of the sulfinyl oxygen atom occurs when ortho-sulfinylbenzyl carbanions are treated with trimethylsilyl halides. The reaction proceeds in good yield and affords optically pure benzyl alcohols withextremely high enantioselectivity (ee > 98%).

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