Food Analysis on Microfluidic Devices Using Ultrasensitive Carbon Nanotubes Detectors

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• 作者：A. Gonzá ; lez Crevillé ; n ; Mó ; nica Á ; vila ; Martin Pumera ; Mar&iacute ; a Cristina Gonzá ; lez ; Alberto Escarpa
• 刊名：Analytical Chemistry
• 出版年：2007
• 出版时间：October 1, 2007
• 年：2007
• 卷：79
• 期：19
• 页码：7408 - 7415
• 全文大小：182K
• 年卷期：v.79,no.19(October 1, 2007)
• ISSN：1520-6882

文摘

Microfluidic devices using carbon nanotube (CNT) materials (single-walled and two multiwalled (MWCNT)) for theanalysis of selected analyte groups of significance in foodssuch as dietary antioxidants, water-soluble vitamins,vanilla flavors, and isoflavones involved in representativefood samples have been explored for the first time.Ultrafast separations resulted in well-defined and resolvedpeaks with enhanced voltammetric current in comparisonwith those obtained from unmodified screen-printedelectrodes, turning MWCNT into an ideal material forelectrochemical sensing in food analysis. Resolution wasimproved by a factor of 2, and sensitivity was dramaticallyenhanced with amplification factors toward calibrationslopes from 4- to 16-fold. In both qualitative and quantitative domains, this impressive performance of CNTs integrated on microfluidics allowed solving specific challengesin food environments such as the direct detection ofanalytes in complex natural samples and unambiguousanalytes in the control of fraud, which was not possibleon nonmodified surfaces, avoiding the integration ofcomplex preconcentration steps on these microdevices.The use of these unique materials in microfluidics for foodanalysis has opened new expectations in "lab-on-a-chip"domains.