C-26 and C-30 Apocarotenoids from Seeds of Ditaxis heterantha with Antioxidant Activity and Protection against DNA Oxidative Damage
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- 作者：Marí ; a D. Mé ; ndez-Robles ; Herry H. Permady ; Marí ; a E. Jaramillo-Flores ; Eugenia C. Lugo-Cervantes ; Anaberta Cardador-Martí ; nez ; Alejandro A. Canales-Aguirre ; Fernando Ló
- 刊名：Journal of Natural Products
- 出版年：2006
- 出版时间：August 2006
- 年：2006
- 卷：69
- 期：8
- 页码：1140 - 1144
- 全文大小：122K
- 年卷期：v.69,no.8(August 2006)
- ISSN：1520-6025
文摘
The hexane extracts of seeds of Ditaxis heterantha afforded two new apocarotenoids whose structures corresponded tomethyl 3-oxo-12'-apo-
-caroten-12'-oate (1) (heteranthin) and methyl 3
,6-epoxy-5-hydroxy-4,5-dihydro-8'-apo--caroten-8'-oate (2) (ditaxin). Both compounds were evaluated for antioxidant activity and protection against DNA oxidativedamage by using DPPH
free radical scavenging and Comet assays, respectively.
-caroten-12'-oate (1) (heteranthin) and methyl 3,6-epoxy-5-hydroxy-4,5-dihydro-8'-apo--caroten-8'-oate (2) (ditaxin). Both compounds were evaluated for antioxidant activity and protection against DNA oxidativedamage by using DPPH free radical scavenging and Comet assays, respectively.