Oxidative Cycloaddition of 1,1,3,3-Tetramethyldisiloxane to Alkynes Catalyzed by Supported Gold Nanoparticles

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• 作者：Ioannis N. Lykakis ; Androniki Psyllaki ; Manolis Stratakis
• 刊名：Journal of the American Chemical Society
• 出版年：2011
• 出版时间：July 13, 2011
• 年：2011
• 卷：133
• 期：27
• 页码：10426-10429
• 全文大小：738K
• 年卷期：v.133,no.27(July 13, 2011)
• ISSN：1520-5126

文摘

Gold nanoparticles supported on TiO₂ (0.1鈥?% mol) catalyze at room temperature and at extremely mild conditions the unprecedented oxidative cycloaddition of 1,1,3,3-tetramethyldisiloxane to alkynes, forming substituted 2,5-dihydro-1,2,5-oxadisiloles, with concomitant evolution of hydrogen gas. For the majority of the substrates, the yields are exceptional (up to 99%). The reaction proceeds at room temperature, tolerates a variety of functional groups, and can be performed in several solvents.