Bilayer Properties of 1,3-Diamidophospholipids
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- 作者：Andreas Weinberger ; Radu Tanasescu ; Cristina Stefaniu ; lllya A. Fedotenko ; France Favarger ; Takashi Ishikawa ; Gerald Brezesinski ; Carlos M. Marques ; Andreas Zumbuehl
- 刊名：Langmuir
- 出版年：2015
- 出版时间：February 17, 2015
- 年：2015
- 卷：31
- 期：6
- 页码：1879-1884
- 全文大小：367K
- ISSN：1520-5827
文摘
A series of 1,3-diamido phosphocholines was synthesized, and their potential to form stable bilayers was investigated. Large and giant unilamellar vesicles produced from these new lipids form a wide variety of faceted liposomes. Factors such as cooling rates and the careful choice of the liposome preparation method influence the formation of facets. Interdigitation was hypothesized as a main factor for the stabilization of facets and effectively monitored by small-angle X-ray scattering measurements.