A One-Pot Approach to 螖2-Isoxazolines from Ketones and Arylacetylenes

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• 作者：Elena Yu. Schmidt ; Inna V. Tatarinova ; Elena V. Ivanova ; Nadezhda V. Zorina ; Igor鈥?A. Ushakov ; Boris A. Trofimov
• 刊名：Organic Letters
• 出版年：2013
• 出版时间：January 4, 2013
• 年：2013
• 卷：15
• 期：1
• 页码：104-107
• 全文大小：237K
• 年卷期：v.15,no.1(January 4, 2013)
• ISSN：1523-7052

文摘

The sequential reaction of ketones with arylacetylenes and hydroxylamine in the presence of KOBu^t/DMSO followed by the treatment of the reaction mixture with H₂O and KOH leads to 螖²-isoxazolines in up to 88% yield.