Regioselective Ring Opening and Isomerization Reactions of 3,4-Epoxyesters Catalyzed by Boron Trifluoride

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• 作者：Javier Izquierdo ; Santiago Rodri虂guez ; Florenci V. Gonza虂lez
• 刊名：Organic Letters
• 出版年：2011
• 出版时间：August 5, 2011
• 年：2011
• 卷：13
• 期：15
• 页码：3856-3859
• 全文大小：763K
• 年卷期：v.13,no.15(August 5, 2011)
• ISSN：1523-7052

文摘

Efficient ring opening of 3,4-epoxyesters with alcohols to produce 4-alkoxy-3-hydroxyesters and their isomerization into 4-ketoesters using boron trifluoride as the catalyst are presented. Both transformations are simple and efficient methods for the synthesis of the above named synthetically useful compounds.