Electron Tomography Shows Molecular Anchoring Within a Layer-by-Layer Film
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- 作者：Matthijn R. J. Vos ; Monica Breurken ; Philippe E. L. G. Leclè ; re ; Paul H. H. Bomans ; Felix de Haas ; Peter M. Frederik ; John A. Jansen ; Roeland J. M. Nolte ; Nico A. J. M. Sommerdijk
- 刊名：Journal of the American Chemical Society
- 出版年：2008
- 出版时间：September 24, 2008
- 年：2008
- 卷：130
- 期：38
- 页码：12608-12609
- 全文大小：161K
- 年卷期：v.130,no.38(September 24, 2008)
- ISSN：1520-5126
文摘
The layer-by-layer self-assembly of thin films consisting of alternating layers of DNA and bis-urea nanoribbons prevents diffusion of the components within the film and allows the anchoring of biotinylated molecules through molecular recognition in a predetermined layer of the film. Electron tomography demonstrates with nanometer precision the location of gold-labeled streptavidin bound to the incorporated biotinylated molecules.