Preparation of a Stable Trifluoroborate Salt for the Synthesis of 1-Aryl-2,2-difluoro-enolethers and/or 2,2-Difluoro-1-aryl-ketones via Palladium-Mediated Cross-Coupling

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• 作者：Jason D. Katz ; Blair T. Lapointe ; Christopher J. Dinsmore
• 刊名：Journal of Organic Chemistry
• 出版年：2009
• 出版时间：November 20, 2009
• 年：2009
• 卷：74
• 期：22
• 页码：8866-8869
• 全文大小：728K
• 年卷期：v.74,no.22(November 20, 2009)
• ISSN：1520-6904

文摘

A bench-stable potassium trifluoroborate enol ether reagent has been prepared. This reagent is suitable for the incorporation of 2,2-difluoroenolethers into aryl and heteroaryl systems via palladium-mediated cross-coupling with suitable halide coupling partners.