Broad Scope Aminocyclization of Enynes with Cationic JohnPhos–Gold(I) Complex as the Catalyst

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• 作者：Ricarda Miller ; Javier Carreras ; Michael E. Muratore ; Morgane Gaydou ; Francesco Camponovo ; Antonio M. Echavarren
• 刊名：Journal of Organic Chemistry
• 出版年：2016
• 出版时间：March 4, 2016
• 年：2016
• 卷：81
• 期：5
• 页码：1839-1849
• 全文大小：464K
• ISSN：1520-6904

文摘

A practical aminocyclization of 1,6-enynes with a wide variety of substituted anilines, including N-alkyl anilines, has been achived by using cationic [JohnPhosAu(MeCN)]SbF₆ as a general purpose catalyst. The resulting adducts can be easily converted into polycyclic compounds by palladium- and gold-catalyzed reactions.