Copper-/Cobalt-Catalyzed Highly Selective Radical Dioxygenation of Alkenes

详细信息    查看全文

• 作者：Qingquan Lu ; Zhiliang Liu ; Yi Luo ; Guanghui Zhang ; Zhiyuan Huang ; Huamin Wang ; Chao Liu ; Jeffrey T. Miller ; Aiwen Lei
• 刊名：Organic Letters
• 出版年：2015
• 出版时间：July 17, 2015
• 年：2015
• 卷：17
• 期：14
• 页码：3402-3405
• 全文大小：335K
• ISSN：1523-7052

文摘

A highly selective radical dioxygenation of alkenes using hydroxamic acid and O₂ was developed, and copper/cobalt was used as the catalyst without assistance of any additional ligands or bases. Mechanistic investigation disclosed that copper salt and O₂ work in concert to activate hydroxamic acid, with Cu(I) and Cu(II) concurrently existing in this reaction.