Contribution of Particle-Size-Fractionated Airborne Lead to Blood Lead during the National Health and Nutrition Examination Survey, 1999–2008

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• 作者：Qingyu Meng ; Jennifer Richmond-Bryant ; J. Allen Davis ; Jonathan Cohen ; David Svendsgaard ; James S. Brown ; Lauren Tuttle ; Heidi Hubbard ; Joann Rice ; Lisa Vinikoor-Imler ; Jason D. Sacks ; Ellen Kirrane ; Dennis Kotchmar ; Erin Hines ; Mary Ross
• 刊名：Environmental Science & Technology
• 出版年：2014
• 出版时间：January 21, 2014
• 年：2014
• 卷：48
• 期：2
• 页码：1263-1270
• 全文大小：296K
• ISSN：1520-5851

文摘

The objective of this work is to examine associations between blood lead (PbB) and air lead (PbA) in particulate matter measured at different size cuts by use of PbB concentrations from the National Health and Nutrition Examination Survey and PbA concentrations from the U.S. Environmental Protection Agency for 1999鈥?008. Three size fractions of particle-bound PbA (TSP, PM₁₀, and PM_2.5) data with different averaging times (current and past 90-day average) were utilized. A multilevel linear mixed effect model was used to characterize the PbB鈥揚bA relationship. At 0.15 渭g/m³, a unit decrease in PbA in PM₁₀ was significantly associated with a decrease in PbB of 0.3鈥?.2 渭g/dL across age groups and averaging times. For PbA in PM_2.5 and TSP, slopes were generally positive but not significant. PbB levels were more sensitive to the change in PbA concentrations for children (1鈥? and 6鈥?1 years) and older adults (鈮?0 years) than teenagers (12鈥?9 years) and adults (20鈥?9 years). For the years following the phase-out of Pb in gasoline and a resulting upward shift in the PbA particle size distribution, PbA in PM₁₀ was a statistically significant predictor of PbB. The results also suggest that age could affect the PbB鈥揚bA association, with children having higher sensitivity than adults.