Study on the Nitric Oxide Scavenging Effects of Ginseng and Its Compounds
详细信息 查看全文
- 作者：Ki Sung Kang ; Takako Yokozawa ; Hyun Young Kim ; and Jeong Hill Park
- 刊名：Journal of Agricultural and Food Chemistry
- 出版年：2006
- 出版时间：April 5, 2006
- 年：2006
- 卷：54
- 期：7
- 页码：2558 - 2562
- 全文大小：71K
- 年卷期：v.54,no.7(April 5, 2006)
- ISSN：1520-5118
文摘
In this study, an in vitro nitric oxide (
NO)-generating system was used to investigate theNO-scavenging effects of methanolic extracts of white ginseng (Panax ginseng C.A. Meyer), redginseng, and sun ginseng and several ginsenosides and phenolic compounds. Sun ginseng extractshowed the strongest activity among the three ginseng extracts. None of the ginsenosides used inthis experiment showed NO-scavenging activity, but the phenolic compounds, such as p-coumaricand vanillic acids, and maltol inhibited NO production in a concentration-dependent manner. Moreover,maltol levels markedly increased by heat processing. Therefore, the enhanced NO-scavenging activityof ginseng by heat processing was closely related to phenolic acids and the increased content ofmaltol.Keywords: White ginseng; red ginseng; sun ginseng; nitric oxide; ginsenoside; phenolic compound
NO)-generating system was used to investigate theNO-scavenging effects of methanolic extracts of white ginseng (Panax ginseng C.A. Meyer), redginseng, and sun ginseng and several ginsenosides and phenolic compounds. Sun ginseng extractshowed the strongest activity among the three ginseng extracts. None of the ginsenosides used inthis experiment showed NO-scavenging activity, but the phenolic compounds, such as p-coumaricand vanillic acids, and maltol inhibited NO production in a concentration-dependent manner. Moreover,maltol levels markedly increased by heat processing. Therefore, the enhanced NO-scavenging activityof ginseng by heat processing was closely related to phenolic acids and the increased content ofmaltol.Keywords: White ginseng; red ginseng; sun ginseng; nitric oxide; ginsenoside; phenolic compound