Establishing a Quantitative Definition of Quorum Sensing Provides Insight into the Information Content of the Autoinducer Signals in Vibrio harveyi and Escherichia coli

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• 作者：Jessica R. Gooding ; Amanda L. May ; Kathryn R. Hilliard ; Shawn R. Campagna
• 刊名：Biochemistry
• 出版年：2010
• 出版时间：July 13, 2010
• 年：2010
• 卷：49
• 期：27
• 页码：5621-5623
• 全文大小：707K
• 年卷期：v.49,no.27(July 13, 2010)
• ISSN：1520-4995

文摘

Extracellular autoinducer concentrations in cultures of Vibrio harveyi and Escherichia coli were monitored by liquid chromatography−tandem mass spectrometry to test whether a quantitative definition of quorum sensing could help decipher the information content of these signals. Although V. harveyi was able to keep the autoinducer-2 to cell number ratio constant, the ratio of signal to cell number for V. harveyi autoinducer-1 and E. coli autoinducer-2 varied as the cultures grew. These data indicate that V. harveyi uses autoinducer-2 for quorum sensing, while the other molecules may be used to transmit different information or are influenced by metabolic noise.