Photoelectrochemical Lab-on-Paper Device Based on an Integrated Paper Supercapacitor and Internal Light Source

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• 作者：Lei Ge ; Panpan Wang ; Shenguang Ge ; Nianqiang Li ; Jinghua Yu ; Mei Yan ; Jiadong Huang
• 刊名：Analytical Chemistry
• 出版年：2013
• 出版时间：April 16, 2013
• 年：2013
• 卷：85
• 期：8
• 页码：3961-3970
• 全文大小：475K
• 年卷期：v.85,no.8(April 16, 2013)
• ISSN：1520-6882

文摘

In this work, a photoelectrochemical (PEC) method was introduced into a microfluidic paper-based analytical device (渭-PAD), and thus, a truly low-cost, simple, portable, and disposable microfluidic PEC origami device (渭-PECOD) with an internal chemiluminescence light source and external digital multimeter (DMM) was demonstrated. The PEC responses of this 渭-PECOD were investigated, and the enhancements of photocurrents in 渭-PECOD were observed under both external and internal light sources compared with that on a traditional flat electrode counterpart. As a further amplification of the generated photocurrents, an all-solid-state paper supercapacitor was constructed and integrated into the 渭-PECOD to collect and store the generated photocurrents. The stored electrical energy could be released instantaneously through the DMM to obtain an amplified (13-fold) and DMM-detectable current as well as a higher sensitivity than the direct photocurrent measurement, allowing the expensive and sophisticated electrochemical workstation or lock-in amplifier to be abandoned. As a model, sandwich adenosine triphosphate (ATP)-binding aptamers were taken as molecular reorganization elements on this 渭-PECOD for the sensitive determination of ATP in human serum samples in the linear range from 1.0 pM to 1.0 nM with a detection limit of 0.2 pM. The specificity, reproducibility, and stability of this 渭-PECOD were also investigated.