Bioactive Limonoid and Triterpenoid Constituents of Turraea pubescens
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- 作者：Chun-Mao Yuan ; Gui-Hua Tang ; Yu Zhang ; Xiao-Ying Wang ; Ming-Ming Cao ; Feng Guo ; Yan Li ; Ying-Tong Di ; Shun-Lin Li ; Hui-Ming Hua ; Hong-Ping He ; Xiao-Jiang Hao
- 刊名：Journal of Natural Products
- 出版年：2013
- 出版时间：June 28, 2013
- 年：2013
- 卷：76
- 期：6
- 页码：1166-1174
- 全文大小：310K
- 年卷期：v.76,no.6(June 28, 2013)
- ISSN：1520-6025
文摘
Eleven new limonoids, turrapubins A鈥揔 (1鈥?b>11), and three new triterpenoids (12鈥?b>14), along with 14 known compounds, were isolated from the twigs of Turraea pubescens. The structures of 1鈥?b>14 were elucidated on the basis of NMR and MS analysis. Compounds 12, 16, 18, and 19 exhibited inhibitory activities against lipopolysaccharide-induced nitric oxide production in RAW264.7 cells. In addition, compounds 2, 11, 18, and 26 exhibited inhibitory activities against brine shrimp larvae (Artemia salina) at 100 ppm with the corrected mortality ranging from 81.7% to 100%.