Study of Highly Efficient Bimetallic Ruthenium Tris-bipyridyl ECL Labels for Coreactant System
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- 作者：Shiguo Sun ; Yang Yang ; Fengyu Liu ; Yi Pang ; Jiangli Fan ; Licheng Sun ; Xiaojun Peng
- 刊名：Analytical Chemistry
- 出版年：2009
- 出版时间：December 15, 2009
- 年：2009
- 卷：81
- 期：24
- 页码：10227-10231
- 全文大小：223K
- 年卷期：v.81,no.24(December 15, 2009)
- ISSN：1520-6882
文摘
A series of bimetallic ruthenium complexes [(bpy)2Ru(bpy)(CH2)n(bpy)Ru(bpy)2]4+ (1, where bpy is 2,2′-bipyridinyl, n = 3, 5, 8) for the coreactant electrochemiluminescence (ECL) system have been synthesized. Their ECL property at different working electrode has been studied in 0.1 M phosphate buffer by using tripropylamine (TPrA) and 2-(dibutylamino) ethanol (DBAE) as the coreactant. The results demonstrate that the ECL intensity depends largely on the length of the saturated carbon chain linkage: the longer is the carbon chain, the higher is the ECL intensity. A remarkable ECL enhancement (up to about 25 times), in comparison with the commonly used metallic [Ru(bpy)3]2+, has been observed from 1c (n = 8) at Pt electrode. With 20 mM TPrA, the log of the ECL intensity increases linearly with the log of complex 1c concentrations over the concentration range of 1.0 × 10−16 to 1.0 × 10−6 M at glassy carbon electrode. The detection limit is 1.0 × 10−16 M at a signal-to-noise ratio of 3. This is the highest ECL detection limit for bimetallic system reported until now. The study provides a general methodology to further improve and tune the ECL efficiency by using multimetallic ruthenium complexes.