Domino Approach for the Synthesis of Pyrrolo[1,2-α]pyrazine from Vinyl Azides

详细信息    查看全文

• 作者：Wenteng Chen ; Miao Hu ; Jianwei Wu ; Hongbin Zou ; Yongping Yu
• 刊名：Organic Letters
• 出版年：2010
• 出版时间：September 3, 2010
• 年：2010
• 卷：12
• 期：17
• 页码：3863-3865
• 全文大小：117K
• 年卷期：v.12,no.17(September 3, 2010)
• ISSN：1523-7052

文摘

A domino synthesis of pyrrolo[1,2-α]pyrazine from 1H-2-pyrrolecarbaldehyde and readily synthesized vinyl azides was developed. This reaction proceeded under relatively mild conditions in the presence of base. Additionally, a possible mechanism for the entire sequence is proposed.