Biomimic Redox Driven Ion Transportation in Smart Nanochannels

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• 作者：Yanglei Xu ; Jiaqiao Jiang ; Zheyi Meng ; Qian Zhang ; Xiulin Li ; Jin Zhai
• 刊名：Journal of Physical Chemistry C
• 出版年：2016
• 出版时间：August 11, 2016
• 年：2016
• 卷：120
• 期：31
• 页码：17342-17347
• 全文大小：391K
• 年卷期：0
• ISSN：1932-7455

文摘

Hydrogen peroxide (H₂O₂) affects biological processes by producing cellular signaling to regulate redox reactions in live cells. By redox signaling, Cytochrome C (Cyt C) in mammalian cells is especially distinguishable for H₂O₂ in controlling ion transportation in biological ion channels. To mimic the mechanism for redox-driven in biology, we modified Cyt C, which could bind H₂O₂, on polymer conical nanochannels to form a redox-driven nanosystem. The influence of the different H₂O₂ concentrations on the ion transportation property in the redox-driven nanosystem is investigated and discussed. The theoretical model of this nanosystem based on the Poisson and Nernst–Planck equations is in good agreement with the experimental data. Accordingly, we constitute a biomimetic reversible and repeatable redox-driven smart nanogating system, monitoring the ion transportation process.