Aryne 1,2,3-Trifunctionalization with Aryl Allyl Sulfoxides

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• 作者：Yuanyuan Li ; Dachuan Qiu ; Rongrong Gu ; Junli Wang ; Jiarong Shi ; Yang Li
• 刊名：Journal of the American Chemical Society
• 出版年：2016
• 出版时间：August 31, 2016
• 年：2016
• 卷：138
• 期：34
• 页码：10814-10817
• 全文大小：419K
• 年卷期：0
• ISSN：1520-5126

文摘

An aryne 1,2,3-trisubstitution with aryl allyl sulfoxides is accomplished, featuring an incorporation of C–S, C–O, and C–C bonds on the consecutive positions of a benzene ring. The reaction condition is mild with broad substrate scope. Preliminary mechanistic study suggests a cascade formal [2 + 2] reaction of aryne with S═O bond, an allyl S → O migration, and a Claisen rearrangement.