C–O/C–H Coupling of Polyfluoroarenes with Aryl Carbamates by Cooperative Ni/Cu Catalysis

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• 作者：Yang Wang ; Song-Bai Wu ; Wen-Juan Shi ; Zhang-Jie Shi
• 刊名：Organic Letters
• 出版年：2016
• 出版时间：June 3, 2016
• 年：2016
• 卷：18
• 期：11
• 页码：2548-2551
• 全文大小：395K
• 年卷期：0
• ISSN：1523-7052

文摘

Cross-coupling of polyfluoroarenes with aryl carbamates through the cleavage of both sp² C–O and C–H bonds is reported. The reaction conditions are simple, and only transition-metal catalysts and ligands are essential. Mechanistic studies indicated that Ni catalyst played an important role in activating C–O bond, while the Cu one in activating C–H Bond. The developed system proved to be effective for cross-coupling of terminal alkynes with aryl carbamates.