Solubility of Glycyrrhizin in Supercritical Carbon Dioxide with and without Cosolvent

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• 作者：Jing-fu Jia ; Fatemeh Zabihi ; Ya-hui Gao ; Ya-ping Zhao
• 刊名：Journal of Chemical & Engineering Data
• 出版年：2015
• 出版时间：June 11, 2015
• 年：2015
• 卷：60
• 期：6
• 页码：1744-1749
• 全文大小：332K
• ISSN：1520-5134

文摘

The solubility of glycyrrhizin in supercritical carbon dioxide (SCCO₂) with cosolvent ethanol at the mole fraction of (0, 0.02, and 0.04) was measured, respectively, at pressures of (9 to 21) MPa and temperatures of (308, 318, and 328) K. The results revealed that the glycyrrhizin solubility depended on the pressure, temperature, and cosolvent mole fraction. The glycyrrhizin solubility in pure SCCO₂ was well correlated with Chrastil, Bartle, and Mendez-Santiago and Teja models with the average absolute relative deviation (AARD) below 6.82 %. The glycyrrhizin solubility in SCCO₂ with cosolvent was correlated by Chrastil modified by Gonz谩lez (Chrastil-G), and MST modified by Sauseau (MST-S) models with satisfactory AARD below 3.85 %. The results provide fundamental data in designing extraction of glycyrrhizin from the licorice or preparation of its particle using SCCO₂ techniques.