Ortho-Dearomatization of Phenols Creating All-Carbon Spiro-Bicycles

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• 作者：Chao Zheng ; Lu Wang ; Jingjie Li ; Leifeng Wang ; David Zhigang Wang
• 刊名：Organic Letters
• 出版年：2013
• 出版时间：August 16, 2013
• 年：2013
• 卷：15
• 期：16
• 页码：4046-4049
• 全文大小：356K
• 年卷期：v.15,no.16(August 16, 2013)
• ISSN：1523-7052

文摘

A range of alkene-linked phenols are generally and reliably dearomatized specifically at their ortho-positions to create all-carbon quaternary stereogenic centers at the corresponding spiro-ring junctions, thus establishing a viable solution to the long-standing synthetic challenge.