Regioselective Decarboxylative Direct C鈥揌 Arylation of Boron Dipyrromethenes (BODIPYs) at 2,6-Positions: A Facile Access to a Diversity-Oriented BODIPY Library

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• 作者：Liang Luo ; Di Wu ; Wei Li ; Shuai Zhang ; Yuanhong Ma ; Su Yan ; Jingsong You
• 刊名：Organic Letters
• 出版年：2014
• 出版时间：December 5, 2014
• 年：2014
• 卷：16
• 期：23
• 页码：6080-6083
• 全文大小：405K
• ISSN：1523-7052

文摘

A palladium-catalyzed regioselective decarboxylative direct C鈥揌 arylation of boron dipyrromethenes (BODIPYs) at the 2,6-positions has been developed as a late-stage approach to rapidly assemble a diversity-oriented BODIPY library. With the complement of this protocol, the direct C鈥揌 arylation of BODIPYs becomes regiocontrollable at 伪- and 尾-positions. A new type of indole-fused BODIPY exhibiting bright red/NIR fluorescence with a large molar extinction coefficient (145鈥?00 M^鈥? cm^鈥?) and a high quantum yield (71%) has been synthesized for the first time.