文摘
Stereoselective synthesis of d-5-homo-4-selenoribose, serving as a versatile intermediate for the synthesis of 4鈥?selenonucleosides 12a鈥?b>c, was accomplished using Sharpless asymmetric epoxidation, regioselective cleavage of the 伪,尾-epoxide, and stereoselective reduction of the ketone as the key steps.