Synthesis of Polysubstituted Furans via Copper-Mediated Annulation of Alkyl Ketones with 伪,尾-Unsaturated Carboxylic Acids

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• 作者：Yuzhu Yang ; Jinzhong Yao ; Yuhong Zhang
• 刊名：Organic Letters
• 出版年：2013
• 出版时间：July 5, 2013
• 年：2013
• 卷：15
• 期：13
• 页码：3206-3209
• 全文大小：275K
• 年卷期：v.15,no.13(July 5, 2013)
• ISSN：1523-7052

文摘

A novel copper-mediated annulation of alkyl ketones with 伪,尾-unsaturated carboxylic acids has been accomplished. This reaction provides a facile and regio-defined method for the synthesis of 2,3,5-trisubstituted furans from simple chemical reagents.