Palladium and Raney Nickel Catalyzed Methanolic Cleavage of Stable Borane-Amine Complexes

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• 作者：Michel Couturier ; John L. Tucker ; Brian M. Andresen ; Pascal Dub&eacute ; and Joanna T. Negri
• 刊名：Organic Letters
• 出版年：2001
• 出版时间：February 8, 2001
• 年：2001
• 卷：3
• 期：3
• 页码：465 - 467
• 全文大小：42K
• 年卷期：v.3,no.3(February 8, 2001)
• ISSN：1523-7052

文摘

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Palladium and Raney nickel were found to catalyze the methanolysis of borane-amine adducts. Hence, strongly complexed amines can nowbe liberated by simple treatment with Pd/C or Raney Ni in methanol. The method is applicable to primary, secondary, tertiary, and aromaticamines, and the mildness of the reaction conditions allows preservation of otherwise labile functional groups.

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