文摘
The depressurization of an expanded liquid organic solution (DELOS) crystallization technique is anew eco-efficient, one-step process for the straightforward production of submicron- or micron-sized crystallineparticles. This novel method is based upon the large, fast, and very homogeneous temperature decreases experiencedby an organic solution, previously expanded with a gaslike compressed fluid (e.g., CO2), when it is depressurized.Through a DELOS process, it is possible to achieve the size reduction of different kinds of organic compounds thatare difficult to comminute by conventional techniques.