Boron-Selective Biaryl Coupling Approach to Versatile Dibenzoxaborins and Application to Concise Synthesis of Defucogilvocarcin M
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- 作者：Yuto Sumida ; Ryu Harada ; Tomoe Kato-Sumida ; Kohei Johmoto ; Hidehiro Uekusa ; Takamitsu Hosoya
- 刊名：Organic Letters
- 出版年：2014
- 出版时间：December 5, 2014
- 年：2014
- 卷：16
- 期：23
- 页码：6240-6243
- 全文大小：404K
- ISSN：1523-7052
文摘
An efficient synthetic method for versatile dibenzoxaborins based on boron-selective Suzuki鈥揗iyaura cross-coupling between o-borylphenols and aryl halides or triflates bearing a 1,8-diaminonaphthalene-protected o-boryl group is reported. A short synthesis of defucogilvocarcin M was achieved using the proposed method in combination with several other boron-mediated transformations.