Nanoscale Transport Enables Active Self-Assembly of Millimeter-Scale Wires
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文摘
Active self-assembly processes exploit an energy source to accelerate the movement of building blocks and intermediate structures and modify their interactions. A model system is the assembly of biotinylated microtubules partially coated with streptavidin into linear bundles as they glide on a surface coated with kinesin motor proteins. By tuning the assembly conditions, microtubule bundles with near millimeter length are created, demonstrating that active self-assembly is beneficial if components are too large for diffusive self-assembly but too small for robotic assembly.r>

Keywords:

Self-assembly; active transport; biomolecular motor; nanowire; kinesin; microtubule

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