Fragment-to-Lead Medicinal Chemistry Publications in 2015

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• 作者：Christopher N. Johnson ; Daniel A. Erlanson ; Christopher W. Murray ; David C. Rees
• 刊名：Journal of Medicinal Chemistry
• 出版年：2017
• 出版时间：January 12, 2017
• 年：2017
• 卷：60
• 期：1
• 页码：89-99
• 全文大小：1024K
• ISSN：1520-4804

文摘

Fragment-based drug discovery (FBDD) is now well-established as a technology for generating new chemical leads and drugs. This Miniperspective provides a tabulated overview of the fragment-to-lead literature published in the year 2015, together with a commentary on trends observed across the FBDD field during this time. It is hoped that this tabulated summary will provide a useful point of reference for both FBDD practitioners and the wider medicinal chemistry community.