Vacuum Ultraviolet Detector for Gas Chromatography

详细信息    查看全文

• 作者：Kevin A. Schug ; Ian Sawicki ; Doug D. Carlton ; Jr. ; Hui Fan ; Harold M. McNair ; John P. Nimmo ; Peter Kroll ; Jonathan Smuts ; Phillip Walsh ; Dale Harrison
• 刊名：Analytical Chemistry
• 出版年：2014
• 出版时间：August 19, 2014
• 年：2014
• 卷：86
• 期：16
• 页码：8329-8335
• 全文大小：335K
• ISSN：1520-6882

文摘

Analytical performance characteristics of a new vacuum ultraviolet (VUV) detector for gas chromatography (GC) are reported. GC-VUV was applied to hydrocarbons, fixed gases, polyaromatic hydrocarbons, fatty acids, pesticides, drugs, and estrogens. Applications were chosen to feature the sensitivity and universal detection capabilities of the VUV detector, especially for cases where mass spectrometry performance has been limited. Virtually all chemical species absorb and have unique gas phase absorption cross sections in the approximately 120鈥?40 nm wavelength range monitored. Spectra are presented, along with the ability to use software for deconvolution of overlapping signals. Some comparisons with experimental synchrotron data and computed theoretical spectra show good agreement, although more work is needed on appropriate computational methods to match the simultaneous broadband electronic and vibronic excitation initiated by the deuterium lamp. Quantitative analysis is governed by Beer鈥揕ambert Law relationships. Mass on-column detection limits reported for representatives of different classes of analytes ranged from 15 (benzene) to 246 pg (water). Linear range measured at peak absorption for benzene was 3鈥? orders of magnitude. Importantly, where absorption cross sections are known for analytes, the VUV detector is capable of absolute determination (without calibration) of the number of molecules present in the flow cell in the absence of chemical interferences. This study sets the stage for application of GC-VUV technology across a wide breadth of research areas.