Lanostane Triterpenes from the Fruiting Bodies of Ganoderma lucidum and Their Inhibitory Effects on Adipocyte Differentiation in 3T3-L1 Cells

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• 作者：IkSoo Lee ; JungJu Seo ; JinPyo Kim ; HongJin Kim ; UiJung Youn ; JoonSeok Lee ; HyunJu Jung ; MinKyun Na ; Masao Hattori ; ByungSun Min ; KiHwan Bae
• 刊名：Journal of Natural Products
• 出版年：2010
• 出版时间：February 26, 2010
• 年：2010
• 卷：73
• 期：2
• 页码：172-176
• 全文大小：177K
• 年卷期：v.73,no.2(February 26, 2010)
• ISSN：1520-6025

文摘

Four new lanostane triterpenes, butyl ganoderate A (1), butyl ganoderate B (2), butyl lucidenate N (3), and butyl lucidenate A (4), were isolated from the fruiting bodies of Ganoderma lucidum together with 14 known compounds (5−18). The structures of the new triterpenes were established by extensive spectroscopic studies and chemical evidence. In addition, the inhibitory effect of isolated compounds on adipocyte differentiation in 3T3-L1 cells was examined.