Asymmetric Organocatalytic Wittig [2,3]-Rearrangement of Oxindoles
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- 作者：Maksim Ošeka ; Mariliis Kimm ; Sandra Kaabel ; Ivar Järving ; Kari Rissanen ; Tõnis Kanger
- 刊名：Organic Letters
- 出版年：2016
- 出版时间：March 18, 2016
- 年：2016
- 卷：18
- 期：6
- 页码：1358-1361
- 全文大小：378K
- ISSN：1523-7052
文摘
A highly enantioselective organocatalytic [2,3]-rearrangement of oxindole derivatives is presented. The reaction was catalyzed by squaramide, and this provides access to 3-hydroxy 3-substituted oxindoles in high enantiomeric purities.