Bisnicalaterine A, a Vobasine−Vobasine Bisindole Alkaloid from Hunteria zeylanica
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- 作者：Alfarius E. Nugroho ; Yusuke Hirasawa ; Nobuo Kawahara ; Yukihiro Goda ; Khalijah Awang ; A. Hamid A. Hadi ; Hiroshi Morita
- 刊名：Journal of Natural Products
- 出版年：2009
- 出版时间：August 28, 2009
- 年：2009
- 卷：72
- 期：8
- 页码：1502-1506
- 全文大小：195K
- 年卷期：v.72,no.8(August 28, 2009)
- ISSN：1520-6025
文摘
A new bisindole alkaloid, bisnicalaterine A (1), consisting of two vobasine-type skeletons, and 3-epivobasinol (2) and 3-O-methylepivobasinol (3), with vobasine-type skeletons, were isolated from the leaves of Hunteria zeylanica, and their structures were elucidated on the basis of spectroscopic data and chemical correlation. Bisnicalaterine A showed moderate cytotoxicity against various human cancer cell lines.