Concentrations of Bisphenol A, Bisphenol A Diglycidyl Ether, and Their Derivatives in Canned Foods in Japanese Markets
详细信息 查看全文
- 作者：Jun Yonekubo ; Kazuichi Hayakawa ; Junko Sajiki
- 刊名：Journal of Agricultural and Food Chemistry
- 出版年：2008
- 出版时间：March 26, 2008
- 年：2008
- 卷：56
- 期：6
- 页码：2041 - 2047
- 全文大小：267K
- 年卷期：v.56,no.6(March 26, 2008)
- ISSN：1520-5118
文摘
Bisphenol A (BPA), bisphenol A diglycidyl ether (BADGE), and their derivatives in 38 canned foods sold in Japan were measured using high-performance liquid chromatography–mass spectrometry (LC-MS) and LC−tandem mass spectrometry (LC-MS/MS). BPA, BADGE, BADGE·2H2O, BADGE·HCl·H2O, BADGE·HCl, and BADGE·2HCl were 0–235.4, 0–3.4, 0–247.2, 0.2–196.4, 0–3.0, and 0–25.7 ng/g, respectively, which did not exceed acceptable daily intake for BPA and specific migration limit for BADGEs. BADGE was degraded by 58, 100, 46, and 58% in water (pH 7), 0.01 N HCl (pH 2), 0.01 N NaCl (pH 6.8), and 0.01 N NaCl with acetic acid (pH 2.5), respectively, when it was allowed to stand at 120 °C for 30 min. The prominent derivatives formed were BADGE·2H2O and BADGE·HCl·H2O, which was formed not only in BADGE with added HCl but also in that with NaCl. Acetic acid accelerated the formation of both BADGE·2H2O and BADGE·HCl·H2O in NaCl. No BPA was detected in any simulation samples started from BADGE. The results suggest that BPA and BADGE are independently leached into canned foods and that BADGE is easily changed to more stable compounds such as BADGE·2H2O and BADGE·HCl·H2O by sterilization.