Novel One-Pot Method for Chemoselective Bromination and Sequential Sonogashira Coupling

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• 作者：Noriki Kutsumura ; Kentaro Niwa ; Takao Saito
• 刊名：Organic Letters
• 出版年：2010
• 出版时间：August 6, 2010
• 年：2010
• 卷：12
• 期：15
• 页码：3316-3319
• 全文大小：234K
• 年卷期：v.12,no.15(August 6, 2010)
• ISSN：1523-7052

文摘

An efficient one-pot method for bromination−elimination of allyl alcohol derivatives and sequential Sonogashira coupling has been developed. A highlight of the method is chemoselective DBU-promoted elimination of vicinal dibromoalkanes having an adjacent O-functional group.