Hypervalent Iodine-Promoted 伪-Fluorination of Acetophenone Derivatives with a Triethylamine路HF Complex

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• 作者：Tsugio Kitamura ; Kensuke Muta ; Kazutaka Muta
• 刊名：Journal of Organic Chemistry
• 出版年：2014
• 出版时间：June 20, 2014
• 年：2014
• 卷：79
• 期：12
• 页码：5842-5846
• 全文大小：277K
• 年卷期：v.79,no.12(June 20, 2014)
• ISSN：1520-6904

文摘

The direct fluorination reaction of acetophenone using iodosylarenes and TEA路5HF was conducted under mild conditions except for use of a HF reagent. The fluorination reaction was applied to acetophenone derivatives, acetonaphthones, benzyl phenyl ketone, propiophenone, butyrophenone, 1-indanone, and phenacyl chloride, giving selectively the corresponding 伪-fluoroketone derivatives in good yields.