Iron-Catalyzed Acylation of Polyfunctionalized Aryl- and Benzylzinc Halides with Acid Chlorides
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- 作者：Andreas D. Benischke ; Marcel Leroux ; Irina Knoll ; Paul Knochel
- 刊名：Organic Letters
- 出版年：2016
- 出版时间：August 5, 2016
- 年：2016
- 卷：18
- 期：15
- 页码：3626-3629
- 全文大小：387K
- 年卷期：0
- ISSN：1523-7052
文摘
FeCl2 (5 mol %) catalyzes a smooth and convenient acylation of functionalized arylzinc halides at 50 °C (2–4 h) and benzylic zinc chlorides at 25 °C (0.5–4 h) with a variety of acid chlorides leading to polyfunctionalized diaryl and aryl heteroaryl ketones.