文摘
A new cobalt-catalyzed phenolic OH-assisted C–H functionalization of 2-vinylphenols with allenes to give various 2H-chromenes is described. It is the first time that allenes are used as the coupling partners in the cobalt-catalyzed C–H activation reactions. In most cases, cobalt-catalyzed oxidative annulation of arenes with alkenes or alkynes via C–H activation gave [4 + 2] or [3 + 2] cyclization products, but the present catalytic reaction afforded an oxidative [5 + 1] cyclization products with the allenes acting as a one-carbon coupling partner. The catalytic reaction is proposed to proceed via the C–H activation of the vinyl group, allene insertion, and an unusual intramolecular regioselective phenoxide addition.