Benzannulation of Indoles to Carbazoles and Its Applications for Syntheses of Carbazole Alkaloids

详细信息    查看全文

• 作者：Xiaojian Zheng ; Leiyang Lv ; Shenglin Lu ; Wenxiao Wang ; Zhiping Li
• 刊名：Organic Letters
• 出版年：2014
• 出版时间：October 3, 2014
• 年：2014
• 卷：16
• 期：19
• 页码：5156-5159
• 全文大小：394K
• ISSN：1523-7052

文摘

A novel and efficient method for the benzannulation of indoles to carbazoles is reported. 纬-Carbonyl tert-butylperoxide is applied as a new diene building block for the 蟺-extension of simple indoles. The synthetic utility of this method is demonstrated by concise and selective total syntheses of naturally occurring carbazole alkaloids, olivacine, and asteropusazole A.