Iron-Catalyzed Convergent Radical Cyclization of Aldehydes with Two Alkenes to 3,4-Dihydropyrans

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• 作者：Leiyang Lv ; Hui Xi ; Xiaohui Bai ; Zhiping Li
• 刊名：Organic Letters
• 出版年：2015
• 出版时间：September 4, 2015
• 年：2015
• 卷：17
• 期：17
• 页码：4324-4327
• 全文大小：412K
• ISSN：1523-7052

文摘

A novel convergent radical cyclization of an aldehyde with two alkenes has been developed. With this method, polyfunctionalized 3,4-dihydropyrans are built in an efficient and selective manner. The iron-catalyzed redox radical recombinations are proposed for the formation of a 3,4-dihydropyran skeleton.