Asymmetric Synthesis of Enaminophosphines via Palladacycle-Catalyzed Addition of Ph2PH to 伪,尾-Unsaturated Imines

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• 作者：Yinhua Huang ; Renta Jonathan Chew ; Sumod A. Pullarkat ; Yongxin Li ; Pak-Hing Leung
• 刊名：The Journal of Organic Chemistry
• 出版年：2012
• 出版时间：August 17, 2012
• 年：2012
• 卷：77
• 期：16
• 页码：6849-6854
• 全文大小：341K
• 年卷期：v.77,no.16(August 17, 2012)
• ISSN：1520-6904

文摘

A highly reactive, chemo- and enantioselective addition of diphenylphosphine to 伪,尾-unsaturated imines catalyzed by a palladacycle has been developed, thus providing the access to a series of chiral tertiary enaminophosphines in high yields. A putative catalytic cycle has also been proposed.