Fast and Selective Extraction of Sulfonamides from Honey Based on Magnetic Molecularly Imprinted Polymer

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• 作者：Ligang Chen ; Xiaopan Zhang ; Lei Sun ; Yang Xu ; Qinglei Zeng ; Hui Wang ; Haoyan Xu ; Aimin Yu ; Hanqi Zhang ; Lan Ding
• 刊名：Journal of Agricultural and Food Chemistry
• 出版年：2009
• 出版时间：November 11, 2009
• 年：2009
• 卷：57
• 期：21
• 页码：10073-10080
• 全文大小：878K
• 年卷期：v.57,no.21(November 11, 2009)
• ISSN：1520-5118

文摘

A fast and selective method was developed for the determination of sulfonamides (SAs) in honey based on magnetic molecularly imprinted polymer. The extraction was carried out by blending and stirring the sample, extraction solvent and polymers. When the extraction was complete, the polymers, along with the captured analytes, were easily separated from the sample matrix by an adscititious magnet. The analytes eluted from the polymers were determined by liquid chromatography−tandem mass spectrometry. Under the optimal conditions, the detection limits of SAs are in the range of 1.5−4.3 ng g⁻¹. The relative standard deviations of intra- and interday ranging from 3.7% to 7.9% and from 4.3% to 9.9% are obtained, respectively. The proposed method was successfully applied to determine SAs including sulfadiazine, sulfamerazine, sulfamethoxydiazine, sulfamonomethoxine, sulfadimethoxine, sulfamethoxazole and sulfaquinoxaline in different honey samples. The recoveries of SAs in these samples from 67.1% to 93.6% were obtained.